Long COVID symptoms research, from brain fog to chronic fatigue : Short Wave : NPR

Tens of millions of persons are affected by lengthy COVID, a illness that encompasses a spread of signs — every part from mind fog to persistent fatigue — and that manifests otherwise throughout sufferers.

The Washington Submit/The Washington Submit by way of Getty Photos


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The Washington Submit/The Washington Submit by way of Getty Photos


Tens of millions of persons are affected by lengthy COVID, a illness that encompasses a spread of signs — every part from mind fog to persistent fatigue — and that manifests otherwise throughout sufferers.

The Washington Submit/The Washington Submit by way of Getty Photos

At a latest Senate listening to on long COVID, Rachel Beale took to the stage and shared her expertise managing her signs for the previous three years. “Lengthy COVID has affected each a part of my life,” mentioned the Virginia resident. “I get up every single day feeling drained, nauseous and dizzy. I instantly begin planning once I can lay down once more.”

Beale is much from alone.

A lot of her experiences have been echoed by others coping with lengthy COVID. It is a constellation of debilitating signs that vary from mind fog and intense bodily fatigue to melancholy and anxiousness. Many individuals have misplaced months or years to this sickness and describe excessive frustration on the lack of solutions.

Docs, too, really feel unmoored by the shortage of solutions. “You do type of really feel such as you’re out within the wilderness,” says Rasika Karnik, the medical director of UChicago Medication’s post-COVID. “It is onerous to look a affected person within the eyes and say ‘we’re not fairly certain but’ and to maintain repeating that.”

There are at present no validated remedies for lengthy COVID. There’s not a extensively established biomarker that can be utilized to diagnose it. Care clinics are onerous to get into — and even when you do get in, most scientists imagine this is not only one sickness within the first place.

However there’s new, promising analysis that sheds gentle onto some lengthy COVID signs. In one study on physical fatigue, researchers at Vrije College in Amsterdam in contrast muscle biopsies of sufferers with and with out lengthy COVID and located that the issue lies not with lung or coronary heart functioning, however with the muscle groups’ skills to take up oxygen within the blood.

And one other group of researchers on the College of Pennsylvania have been in a position to pinpoint one potential reason behind mind fog: a drop in serotonin levels. They have been additionally in a position to reverse mind fog signs in mice.

There’s a rising community of scientists who’re pushing analysis ahead — many with personal funding from philanthropists. Congress has allotted greater than a billion {dollars} for lengthy COVID analysis, and there is been some new funding introduced by the NIH lately. However affected person advocates say that fixing an issue of this scale will take continued consideration and much more funding.

Have extra COVID questions you need us to cowl? E-mail us at [email protected] — we might love to listen to from you.

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This episode was produced by Margaret Cirino. It was edited by Brit Hanson and Rebecca Ramirez. David Greenburg was the audio engineer.